20th
conference on
Computational Intelligence methods for Bioinformatics and Biostatistics

September 10 - 12, 2025 in Milano, Italy

About CIBB

The International Conference on Computational Intelligence Methods for Bioinformatics and Biostatistics (CIBB) was established in 2004 through the efforts of its co-founders Roberto Tagliaferri (Università di Salerno, Italy), Francesco Masulli (Università di Genova, Italy), and Antonina Starita (Università di Pisa, Italy). Initially introduced as a special session during the 14th Italian Workshop on Neural Networks (WIRN 2004) in Perugia, Italy, CIBB quickly evolved into an internationally recognized event. For its first four editions, the conference was organized as a special session within various international events held in Italy. In October 2008, CIBB became an independent conference, with its inaugural standalone edition taking place in Vietri sul Mare, Italy. Sadly, this milestone coincided with the passing of Antonina Starita (1939–2008), one of its visionary founders.

CIBB serves as a multidisciplinary platform for researchers exploring the application of Computational Intelligence techniques, broadly defined, to challenging problems in bioinformatics, biostatistics, and medical informatics. Since its foundation, CIBB has produced 13 proceedings books, 4 sections of proceedings books, and 11 journal supplements, amounting to approximately 400 peer-reviewed scientific contributions (see past editions). While traditionally held every two years, CIBB 2023, hosted in Padova, marked a return to in-person gatherings after the virtual format of 2021. The 2024 edition hosted in Benevento marked the start of an annual schedule for CIBB.

CIBB welcomes submissions highlighting emerging trends and future directions at the intersection of computational and life sciences, with particular interest in the application of computational intelligence to systems and synthetic biology. Contributions from theoretical and experimental biologists are highly encouraged to promote interdisciplinary collaboration. Authors are invited to submit short papers (4–6 pages) presenting their original research in areas such as bioinformatics, biostatistics, systems and synthetic biology, and medical informatics. Accepted papers will be featured in plenary oral sessions or dedicated special sessions.

Where

Politecnico di Milano, Campus Leonardo, Building 3 - room 3.0.3,
Piazza Leonardo da Vinci, 32

When

10-12 September 2025

Local Organizers

Data Science and Bioinformatics lab

Department of Electronics, Information and Bioengineering Politecnico di Milano

Research tracks

Main tracks

Bioinformatics

Topics of interest include, but are not limited to:
  • Applications of machine learning to bioinformatics or health datasets
  • Data mining methods in biomedical contexts
  • Artificial intelligence in biomedicine
  • Next-generation sequencing bioalgorithms
  • Multi-omics data analysis
  • Statistical analysis of high-dimensional omics data
  • Algorithms for alternative splicing analysis
  • Methods for visualization of high-dimensional biomedical data
  • Software tools for bioinformatics
  • Methods for comparative genomics
  • Computational tools for proteomics
  • Simulation of biological systems and clinical populations
  • Methods for the functional classification of genes
  • Algorithms for molecular evolution and phylogenetic analysis
  • Methods for unsupervised analysis, validation, and visualization of structures discovered in bio-molecular data
  • Health informatics and medical informatics
  • Biomedical and microscopy imaging
  • Methods for the integration of clinical, genetic, or environmental data
  • Heterogeneous data integration and data fusion
  • Algorithms for pharmacogenomics
  • Biomedical text mining and natural language processing
  • Bayesian methods for medical and biological data
  • Health big data analytics
  • Data-driven approaches for patient stratification, and prognosis or onset prediction
  • Process mining in healthcare
  • Information retrieval, and temporal and spatial representation and reasoning in biomedicine
  • Simulation models, software, and tools (clinical decision support systems, patient engagement support, visual analytics, solutions for assisted living, and telemedicine)
  • Biomedical signal processing
  • Explainable AI and clinical model interpretation
  • Personalised medicine for diagnosis and prognosis
  • Statistical methods for the analysis of clinical data
  • Prediction of secondary and tertiary protein structures
  • Advanced pathway enrichment analysis methods
  • Mass spectrometry data analysis in proteomics
  • Bio-molecular databases and data mining
  • Mathematical modelling and automated reasoning on biological and synthetic systems
  • Computational simulation of biological systems
  • Methods and advances in systems biology
  • Spatio-temporal analysis of synthetic and biological systems
  • Network systems biology
  • Models for cell populations and tissues
  • Methods for the engineering of synthetic components
  • Modelling and engineering of interacting synthetic and biological systems
  • Software tools for bioinformatics, biostatistics, systems and synthetic biology
  • Computational drug discovery
  • Operational research in healthcare and bioinformatics

Biostatistics

Topics of interest include, but are not limited to:
  • Statistical analysis of high-dimensional omics data
  • Methods for comparative genomics
  • Health informatics and medical informatics
  • Bayesian methods for medical and biological data
  • Health big data analytics
  • Data-driven approaches for patient stratification, and prognosis or onset prediction
  • Statistical methods for the analysis of clinical data
  • Advanced pathway enrichment analysis methods

Medical Informatics

Topics of interest include, but are not limited to:
  • Artificial intelligence in biomedicine
  • Health informatics and medical informatics
  • Biomedical and microscopy imaging
  • Methods for the integration of clinical, genetic, or environmental data
  • Heterogeneous data integration and data fusion
  • Biomedical text mining and natural language processing
  • Health big data analytics
  • Information retrieval, and temporal and spatial representation and reasoning in biomedicine
  • Simulation models, software, and tools (clinical decision support systems, patient engagement support, visual analytics, solutions for assisted living, and telemedicine)
  • Explainable AI and clinical model interpretation
  • Personalised medicine for diagnosis and prognosis
  • Process mining in healthcare
  • Computational drug discovery
  • Operational research in healthcare and bioinformatics


Keynote Speakers

Call for Special Session proposals

Main guidelines for Special Session proposers:
  • Proposers will actively promote the conference calls within the research community and contribute to managing the peer review process for their special session together with the general chairs, ensuring consistency and quality across all sessions.
  • Each Special Session must include at least 4 or 5 accepted papers. If fewer papers are accepted, they will be integrated into the conference’s main tracks.
  • A Special Session may feature an invited speaker, pending approval by the Scientific Committee. The invited speaker should be a distinguished expert with significant contributions to the proposed topic.
Proposer restrictions:
  • Proposers cannot be co-authors of more than one-third/half of the papers included in their special session.
  • Special Session chairs (up to two selected from the proposers) cannot present any submitted work in the session they are chairing

Call for short paper submission


We are thrilled to announce the opening of the Call for short paper submission for the upcoming 20th edition of the Computational Intelligence methods for Bioinformatics and Biostatistics (CIBB) conference.

Submission guidelines:

Authors are invited to submit a short paper (4-6 pages) presenting their original research. Paper submissions will be handled through EasyChair platform and detailed instructions on the submission process will be provided later.

Main Tracks and Special Sessions:

In addition to the three main tracks (Bioinformatics, Biostatistics, Medical Informatics), CIBB2025 will feature Special Sessions focusing on emerging and specialized topics. The list of Special Sessions will be soon available on the conference website.

Publication Opportunities:

Submitted contributions will undergo peer review, and all accepted contributions that will be presented at the conference will be invited for submission of extended versions to the Springer Lecture Notes in Bioinformatics (LNBI) or to a selected journal. We are currently discussing this option with Frontiers and BMC (details forthcoming).

Available templates for submission:

Post-conference proceedings and journal papers


After the conference, the authors of all accepted contributions presented at the conference will be invited to submit an extended version of their manuscripts to Lecture Notes or a selected journal. Accordingly, we are currently discussing this option with Frontiers, BMC and Springer Lecture Notes.

journals

Registration

Fees for the conference registration will be published soon.
Visa information

Participants from the European Union do not need a visa to attend the conference.

If you require a visa to travel, an invitation letter can be provided upon request. Please contact the General Chairs at cibb2025@polimi.it for assistance.

Key Dates

February 23, 2025
Special session proposal deadline
March 5, 2025
Call for short papers
April, 2025
Call for posters
April 30, 2025
Short paper and poster submission deadline
June 15, 2025
Registration opens
June 23-30, 2025
Call for late posters and published works
June 23-30, 2025
Short paper and poster acceptance/rejection notification
July 6, 2025
Short paper camera-ready submission deadline
July 11, 2025
Short paper final acceptance/rejection notification
July 18, 2025
Late poster and published work submission deadline
July 25, 2025
Late posters/published works acceptance/rejection notification
August 1, 2025
Early-bird registration deadline
September 4, 2025
Late registration deadline
September 10-12, 2025
Conference
October 15, 2025
Submission of extended paper for LNBI post-conference proceedings deadline
Abstract submission for Journal extended papers deadline
December, 2025
Submission of full manuscript for selected journal deadline

Event Venue

Politecnico di Milano, Campus Leonardo

How to reach us:

The conference venue - Building 3, room 3.0.3 - is at walkable distance from Green Metro line -Piola.
From:
  • Milano Malpensa airport:
    1. Malpensa express shuttle, direction Milano Central, Milano Central stop
    2. Green metro line , direction Gessate, Piola stop
  • Milano Linate airport:
    1. Blue metro line , direction San Cristoforo, Argonne stop
    2. Bus line 90 or 93
  • Milano Stazione Centrale:
    • Green metro line , direction Gessate, Piola stop

Committee

General Chairs


Track Chairs



Steering Committee

  • Roberto Tagliaferri, Università di Salerno, Italy
  • Davide Chicco, University of Toronto, Canada
  • Francesco Masulli, Università di Genova, Italy
  • Elia Biganzoli, Università Statale di Milano, Italy
  • Clelia Di Serio, Università Vita-Salute San Raffaele, Italy
  • Pierre Baldi, University of California Irvine, USA
  • Alexandru Floares, Solutions of Artificial Intelligence Applications Institute, Romania
  • Jon Garibaldi, University of Nottingham, England
  • Nikola Kasabov, Auckland University of Technology, New Zealand
  • Leif Peterson, Rice University, USA

Local Committee

Advisory Board

  • Elia Biganzoli, Università Statale di Milano, Italy
  • Davide Chicco, University of Milano Bicocca, Italy
  • Francesca Ieva, Politecnico di Milano, Italy
  • Giulio Pavesi, Università Statale di Milano, Italy
  • Erika Salvi, Fondazione IRCCS Istituto Neurologico “Carlo Besta”, Italy
  • Paolo Verderio, Fondazione IRCCS Istituto Nazionale dei Tumori, Italy

Programme Committee

  • Giuseppe Agapito, Università Magna Graecia di Catanzaro, Italy
  • Helena Aidos, University of Lisbon, Portugal
  • Abbas Alameer, Kuwait University, Kuwait
  • Luca Alessandri, University of Torino, Italy
  • Claudia Angelini, Institute for Applied Mathematics of the National Council for Research (IAC-CNR), Italy
  • Claudio Angione, Teesside University, UK
  • Antonino Aparo, University of Verona, Italy
  • Michele Atzeni, University of Padova, Italy
  • Riccardo Aucello, University of Torino, Italy
  • Sansanee Auephanwiriyakul, Chiang Mai University, Thailand
  • Simone Avesani, University of Verona, Italy
  • Daniele Baccega, University of Torino, Italy
  • Matteo Baldan, University of Padova, Italy
  • Ileana Baldi, University of Padova, Italy
  • Krzysztof Bartoszek, Linkoping University, Sweden
  • Giacomo Baruzzo, University of Padova, Italy
  • Petra Baumann, Medical University of Graz, Austria
  • Marco Beccuti, University of Torino, Italy
  • Massimo Bellato, University of Padova, Italy
  • Pietro Belloni, University of Padova, Italy
  • Anna Bernasconi, Politecnico di Milano, Italy
  • Gilles Bernot, University of Nice Sophia Antipolis, France
  • Giovanni Birolo, University of Torino, Italy
  • Vincenzo Bonnici, University of Parma, Italy
  • Pietro Bosoni, University of Pavia, Italy
  • Davide Bressan, University of Trento, Italy
  • Maria Fernanda Cabrera-Umpierrez, Universidad Politécnica de Madrid, Spain
  • Salvatore Calderaro, University of Palermo, Italy
  • Nunzio Camerlingo, Pfizer, Inc., USA
  • Andrea Campagner, University of Milano-Bicocca, Italy
  • Giacomo Cappon, University of Padova, Italy
  • Annamaria Carissimo, Institute for Applied Mathematics of the National Council for Research (IAC-CNR), Italy
  • Giuseppe Cattaneo, Università di Salerno, Italy
  • Filippo Causa, University of Naples, Italy
  • Paolo Cazzaniga, University of Bergamo, Italy
  • Matteo Cesari, Medical University of Innsbruck, Austria
  • Giulia Cesaro, University of Padova, Italy
  • Yuwen Chen, University of Cambridge, UK
  • Davide Chicco, University of Toronto, Canada
  • Giovanni Cicceri, University of Palermo, Italy
  • Matteo Comin, University of Padova, Italy
  • Rosanna Comoretto, University of Torino, Italy
  • Corrado Coppola, Sapienza University of Rome, Italy
  • Anna Livia Croella, Sapienza University of Rome, Italy
  • Fabio Cumbo, Cleveland Clinic, USA
  • Luisa Cutillo, University of Leeds, UK
  • Chiara Damiani, University of Milano-Bicocca, Italy
  • David Dannhauser, University of Naples, Italy (Federico II), Italy
  • Pierluigi Francesco De Paola, IEIIT National Research Council (CNR), Italy
  • Barbara Di Camillo, University of Padova, Italy
  • Giorgio Maria Di Nunzio, University of Padova, Italy
  • Lorenzo Di Rocco, Sapienza University of Rome, Italy
  • Guglielmo Faggioli, University of Padova, Italy
  • Piero Fariselli, University of Torino, Italy
  • Carlo Ferrari, University of Padova, Italy
  • Umberto Ferraro Petrillo, Sapienza University of Rome, Italy
  • Christoph M. Friedrich, University of Applied Sciences and Arts Dortmund, Germany
  • Alessio Funari, Sapienza University of Rome, Italy
  • Bruno Giovanni Galuzzi, University of Milano-Bicocca, Italy
  • Gennaro Gambardella, Telethon Institute of Genetics and Medicine (TIGEM), Italy
  • Roberto Gatta, University of Brescia, Italy
  • Francesco Gentile, University of Catanzaro, Italy
  • Eleni Georga, University of Ioannina, Greece
  • Filippo Geraci, Institute for Informatics and Telematics of C.N.R., Italy
  • Raffaele Giancarlo, Università di Palermo, Italy
  • Alberto Giaretta, University of Cambridge, UK
  • Rosalba Giugno, University of Verona, Italy, Italy
  • Yair Goldberg, Israel Institute of Technology, Israel
  • Giorgio Grani, Sapienza University of Rome, Italy
  • Alessandra Grossi, University of Milano-Bicocca, Italy
  • Alessandro Guazzo, University of Padova, Italy
  • Henrik Imberg, University of Gothenburg, Germany
  • Giuseppe Jurman, Fondazione Bruno Kessler, Italy
  • Corrado Lanera, University of Padova, Italy
  • Youngro Lee, Seoul National University, South Korea
  • Nicola Licheri, University of Torino, Italy
  • Giosue Lo Bosco, University of Palermo, Italy
  • Enrico Longato, University of Padova, Italy
  • Francesca Longhin, University of Padova, Italy
  • Marta Lovino, Politecnico di Torino, Italy
  • Zeinab Mahmoudi, Department of Pharmacometrics, Novo Nordisk, Denmark
  • Stefano Marchesin, University of Padova, Italy
  • Glen Martin, The University of Manchester, UK
  • Andreia Martins, University of Lisbon, Portugal
  • Francesca Marturano, Harvard University, USA
  • Carlotta Maschiocchi, Fondazione Policlinico Universitario Gemelli, Italy
  • Giancarlo Mauri, University of Milano-Bicocca, Italy
  • Claudia Mengoni, University of Verona, Italy
  • Mikele Milia, University of Padova, Italy
  • Carmelo Militello, Institute for High-Performance Computing and Networking, National Research Council (ICAR-CNR), Italy
  • Alexander Monzon, University of Padova, Italy
  • Margherita Mutarelli, National Research Council (CNR), Italy
  • Paolo Antonio Netti, Italian Institute of Technology (CABHC@CRIB), Italy
  • Shahryar Noei, Fondazione Bruno Kessler, Italy
  • Lisa Novello, Fondazione Bruno Kessler, Italy
  • Stefania Orini, University of Brescia, Italy, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy
  • Alessia Paglialonga, IEIIT National Research Council (CNR), Italy
  • Francesco Palini, Sapienza University of Rome, Italy
  • Niels Peek, The University of Manchester, UK
  • Leonardo Pellegrina, University of Padova, Italy
  • Marzio Pennisi, University of Eastern Piedmont, Italy
  • Simone Pernice, University of Turin, Italy
  • Wellington Pinheiro Dos Santos, Universidade Federal de Pernambuco, Brazil
  • Cinzia Pizzi, University of Padova, Italy
  • Marco Podda, University of Pisa, Italy
  • Francesco Prendin, University of Padova, Italy
  • Francesco Prinzi, University of Palermo, Italy
  • João Ribeiro Pinto, INESC TEC and University of Porto, Portugal
  • Dario Righelli, University of Padova, Italy
  • Riccardo Rizzo, Institute for High-Performance Computing and Networking, National Research Council (ICAR-CNR), Italy
  • Aurora Saibene, University of Milano-Bicocca, Italy
  • Tiziana Sanavia, University of Torino, Italy
  • Ilie Sarpe, University of Padova, Italy
  • Fabio Scarpa, University of Padova, Italy
  • Rakesh Shiradkar, Emory University, USA
  • Pasquale Sibilio, Sapienza University of Rome, Italy
  • Gianmaria Silvello, University of Padova, Italy
  • Dario Simionato, University of Padova, Italy
  • Diogo Soares, University of Lisbon, Portugal
  • Andrea Sottosanti, University of Padova, Italy
  • Simone Spagnol, Iuav University of Venice, Italy
  • Antonino Staiano, Università di Napoli Parthenope, Italy
  • Roberto Tagliaferri, University of Salerno, Italy
  • Erica Tavazzi, University of Padova, Italy
  • Michele Tebaldi, University of Verona, Italy
  • Irene Terrone, University of Torino, Italy
  • Jacopo Tessadori, Fondazione Bruno Kessler, Italy
  • Manuel Tognon, University of Verona, Italy, Italy
  • Mirko Treccani, University of Verona, Italy
  • Isotta Trescato, University of Padova, Italy
  • Filippo Utro, IBM, USA
  • Filippo Vella, National Research Council of Italy, Italy
  • Laura Veschetti, University of Verona, Italy
  • Martina Vettoretti, University of Padova, Italy
  • Eva Viesi, University of Verona, Italy
  • Veronica Vinciotti, University of Trento, Italy

Past editions

Conference websites

Conference proceeding

Journal supplements

Contacts

Telephone

02 2399 3400

E-mail

cibb2025@polimi.it