ACADEMIC DEGREES
|
|
APPOINTMENTS
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2008-today |
Lecturer
of Bioinformatics and Computational Biology for Molecular Medicine,
Electronics and Information Department, Politecnico di Milano, Milano - Italy |
|
2006-today |
Researcher,
Electronic and Information Department, Politecnico di Milano, Milano - |
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2000-today |
Lecturer
of BioMedical Informatics, Bioengineering Department, Politecnico di Milano,
Milano - |
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1999-2006 |
Research
Assistant, Bioengineering Department, Politecnico di Milano, Milano - |
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1996-1998 |
Post-Doctoral
Fellow, Pathology Department, |
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1994-1995 |
Research
Fellow, Biomedical Engineering Department,
The |
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1993-1996 |
PhD
Student, Pathology Department, |
|
1991-1993 |
Researcher,
Pharmacological Research Institute "
Mario Negri", Milano - Italy |
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1990-1991 |
Research
Fellow, Molecular Graphics Suite, |
HONORARY APPOINTMENTS
1992
Visiting
Professor, Pathology Department,
RESEARCH INTERESTS
Bioinformatics,
medical informatics, biomedical data analysis, distributed web
applications and databases,
image processing.
ACADEMIC TEACHING
Courses
|
2008-today |
Professor
of the course “Bioinformatics
and Computational Biology for Molecular Medicine”, Master degree in Computer Science Engineering, Politecnico
di Milano, Milano – |
|
2004-today |
Professor of the course “Management of clinical data and international
standards” of the ESF one year Master in “Informatics processing
of biomedical data and telecontrol in Medicine”, University of Verona, Verona - Italy |
|
2003-today |
Professor of the course “Laboratory of BioMedical Informatics and Distributed Systems”, Master
degree in Biomedical Engineering, Politecnico di Milano, Milano - |
|
2003-today |
Professor of the course “Laboratory of Internet application building for
medicine in healthcare” of the ESF one year course for the training of
“Expert Technicians in Medical Informatics”, Politecnico di
Milano, Milano - |
|
2002-2004 |
Coordinator
of the module “Infrastructures for Telemedicine” within the ESF Telemedicine Master course of
“Internet
for Health Care and Medicine”, Cefriel - Politecnico di Milano,
Milano - |
|
2002 |
Lecturer
within the PhD course “Advanced Health Information Systems”, PhD
in Biomedical Engineering, Politecnico di Milano, Milano - |
|
2002-2004 |
Lecturer
of tutorials on Genomics data banks, Web access to remote databases, Software
agents, Biomedical vocabularies and language systems, Bioimage archives,
Medical image and Clinical data integration, within the ESF Telemedicine Master course
“Internet
for Health Care and Medicine”, Cefriel - Politecnico di Milano,
Milano - Italy |
|
2000-2003 |
Professor
of the course “Medical Informatics III (laboratory)”,
Master degree in Biomedical Engineering, Politecnico di Milano, Milano - Italy |
|
2000-2002 |
Lecturer and coordinator of the one
week course "Seminars on Practical Clinical Informatics and on Basic
Medical Statistics", International
Academy of Bergamo for Advanced
Medical Sciences and International Heart School, Bergamo - Italy |
|
2000-2002 |
Lecturer
of the practical lessons within the course “Medical Informatics”,
Bachelor degree in Biomedical Engineering, Politecnico di Milano, Milano -
Italy |
|
2000 |
Lecturer within the module
“Medical Informatics” of the ESF "Course for the training of
Expert Technicians in Planning, Control, and Management of Sanitary
Environments and Products", Politecnico di Milano, Milano - Italy |
|
1999-2002 |
Lecturer
of tutorial on Videomicroscopy and Image Processing within the course
“Bioimaging”, Master degree in Biomedical Engineering,
Politecnico di Milano, Milano - Italy |
·
2008-
2013
·
2007- 2010
·
2007
·
2007
·
2003-
2006
·
1999-2000
·
1995-1998 "Immunehistochemical and
digital image analysis study of the glomerulusclerosis and renal
tubuleinterstitial lesions associated with aging", Collaborator for the University of
Granada, Granata – Spain.
·
2000-2002 "Development of algorithms
and tools for microarray data management and analysis", Collaborator for the European
Institute of Oncology, Milano –
1995-1998 Member of the Research Group CTS138 in
Health Science and Technology of the Andalusian
2006 “Visiting
scholar program fellowship” from
2004 e 2005 “Visiting
faculty exchange program fellowship” of the National Library of Medicine, National Institute of Health, for six
months, for the application of Natural
Language Processing techniques on Medline abstract of scientific publications
in order to automatically extract gene-gene and gene-disease semantic
relations, and for the post-processing of extracted information with the aim of
inferring unknown gene-gene and gene-disease relations.
2004 Selection, within the evaluation of Italian University Scientific Research, of the scientific publication Masseroli M, Cerveri P, Pelicci PG, Alcalay M. GAAS: “Gene Array Analyzer Software for management, analysis and visualization of gene expression data” Bioinformatics 2003;19(6):774-775 and the correspondent web tool (http://www.bioinformatics.polimi.i/GAAS/), as one of the best 7 research products of the Bioengineering Department of the Politecnico di Milano in the years 2001-2003.
2000 “Best scientific
publication in basic investigation - year
1996 European
Post-Doctoral Fellowship from the Spanish
board of science and technology "Comisión Interministerial de Ciencia y
Tecnología (CICYT)" within the “Acciones de Formación de Personal
Investigador - Estancias de Científicos y Tecnólogos Extranjeros en España”
to develop research projects in the field of biomedical image processing.
1994 Fellowship from "Sandoz Pharma S.A.E." to develop image
analysis programs for the quantification of renal fibrosis induced by
Cyclosporin A pharmacological treatment.
1993 “Best
oral communication”, to the communication "Cuantificación
automatizada de la fibrosis renal por análisis digital de imagen",
presented at the "XVI National Congress of the Spanish Society of
Pathology" held in Tenerife - Spain in May 1993.
COPYRIGHT
1995 Member of the Organizing committee "First European Symposium on Current and
Future directions for Clinical Flow Cytometry",
44. Ghisalberti
G, Masseroli M, Tettamanti L. Quality controls in integrative approaches
to detect errors and inconsistencies in biological databases. Journal of Integrative Bioinformatics
2010 (in press).
43. D’Antonio
M, Masseroli M. Extraction, integration and analysis of alternative
splicing and protein structure distributed information. BMC Bioinformatics 2009 Oct 15;10 (Suppl 12):S15, p. 1-8.
42. Masseroli
M, Bachi A, Boschetti E, Righetti PG. Searching for specific motifs in
affinity capture in proteome analysis. Journal
of Proteomics 2009 Jul 21;72(5):791-802.
41. Holst MI,
Maercker C, Pintea B, Masseroli M, Liebig C, Jankowski J, Miething A,
Martini J, Schwaller B, Oberdick J, Schilling K, Baader SL. Engrailed-2 regulates genes
related to vesicle formation and transport in cerebellar Purkinje cells. Molecular
and Cellular Neuroscience 2008 Aug;38(4):495-504.
40. Masseroli M, Marchente M. X-PAT: a multiplatform patient
referral data management system for small healthcare institution requirements. IEEE Transaction on Information Technology
in Biomedicine 2008 Jul;12(4):424-432.
39. Bachi A, Simó C, Restuccia U, Guerrier L, Fortis F, Boschetti E, Masseroli
M, Righetti PG. Performance of combinatorial peptide libraries in capturing
the low-abundance proteome of reb blood cells. II: behaviour of resins
containing individual amino acids. Analytical
Chemistry 2008 May 15;80(10):3557-3565.
38. Ceri S, Bolchini C, Braga D, Brambilla M,
Campi A, Comai S, Fraternali P, Lanzi PL, Masseroli M, Matera M, Negri
M, Pelagatti G, Pozzi G, Quintarelli E, Schreiber FA, Tanca L. Data and web
management research at Politecnico di Milano. ACM SIGMOD
Record
2007 Dec;36(4):43-48.
37. Masseroli M. Management and analysis of genomic functional and phenotypic controlled annotations to support biomedical investigation and practice. IEEE Transaction on Information Technology in Biomedicine 2007 Jul;11(4):376-385.
36. Del Moral FG,
O’Valle F, Masseroli M, Del Moral RG. Image analysis application
for automatic quantification of intramuscular connective tissue in meat. Journal of Food Engineering 2007
Jul;81(1):33–41.
35. Masseroli M, Bellistri E, Franceschini A, Pinciroli F. Statistical analysis of genomic protein family and domain controlled annotations for functional investigation of classified gene lists. BMC Bioinformatics 2007 March 8;8(Suppl 1):S14, p. 1-10.
34. Masseroli M, Pinciroli F. BioInformatics application service providers of Politecnico di Milano. Healthcare IT Management, the official Journal of the European Association of Healthcare IT Managers 2006 Summer;1(2):42-44.
33. Masseroli M, Kilicoglu H, Lang F-M,
Rindflesch TC. Argument-predicate distance as a filter for enhancing
precision in extracting predications on the genetic etiology of disease. BMC
Bioinformatic 2006 Jun 8;7(1):291, p. 1-12.
32. Masseroli M,
Pinciroli F. Using Gene Ontology and genomic controlled vocabularies to analyze
high-throughput gene lists: three tool comparison. Computers in Biology and
Medicine 2006 Jul-Aug;36(7-8):731-747.
31. Masseroli M, Visconti A, Bano SG,
Pinciroli F. He@lthCo-op: a web-based system to support distributed healthcare
co-operative work. Computers
in Biology and Medicine 2006
Feb;36(2):109-127.
30. Masseroli M, Galati O, Manzotti M,
Gibert K, Pinciroli F. Inherited disorder phenotypes: controlled annotation and
statistical analysis for knowledge mining from gene lists. BMC
Bioinformatics 2005;6(Suppl 4):S18, p. 1-8.
29. Burgarella S, Cattaneo D, Pinciroli F, Masseroli M. MicroGen: a MIAME compliant web
system for microarray experiment information and workflow management. BMC Bioinformatics 2005;6(Suppl 4):S6, p. 1-6.
28. Masseroli M, Stella A, Alcalay M, Pinciroli F. GeneWebEx: Gene annotation Web Extraction, aggregation, and updating from web-interfaced biomolecular databanks. International Journal of Software Engineering and Knowledge Engineering 2005;15(3):511-526.
27. Masseroli M, Galati O, Pinciroli F. GFINDer: genetic disease and
phenotype location statistical analysis and mining of dynamically annotated
gene lists. Nucleic Acids
Research 2005;33:W717-W723.
26. Masseroli M,
Stella A, Meani N,
Alcalay M, Pinciroli F. MyWEST: My Web Extraction Software Tool
for effective mining of annotations from web-based databanks.
Bioinformatics 2004;20(18):3326-3335.
25. Masseroli M, Martucci
D, Pinciroli F. GFINDer: Genome Function INtegrated Discoverer through dynamic
annotation, statistical analysis, and mining. Nucleic Acids Research 2004;32:W293-W300.
24. Masseroli M, Cerveri P, Pelicci PG, Pinciroli F, Alcalay M. Gene Array Analyzer Software: a multi-user platform for management, analysis and visualization of gene expression data from replicate experiments. Minerva Biotecnologica 2003;15(4):207-216.
23. Pinciroli F, Masseroli M, Tognola G. The educational offer in Medical Informatics and Telemedicine at the Engineering Faculty of the Politecnico di Milano. IEEE Transaction on Education 2003;46(3):394-398.
22. Masseroli M, Cerveri P, Pelicci PG, Alcalay M. GAAS: Gene Array Analyzer Software for management, analysis and visualization of gene expression data. Bioinformatics 2003;19(6):774-775.
21. Caballero T, Pérez-Milena A, Masseroli
M, O'Valle F, Salmerón FJ, Del Moral RMG, Sánchez-Salgado G. Liver fibrosis assessment with
semiquantitative indexes and image analysis quantification in sustained-responder and non-responder interferon-treated
patients with chronic hepatitis C. Journal
Hepatology 2001;34(5):740-747.
20. Arrebola
Vargas F, Masseroli M, Reguero Callejas ME, Mesa Aguado FL, Olmo Sevilla
A, Aguilar Peña M, Espigares Fuentes B, Del Moral Garrido RG, O'Valle Ravassa
F.
Procedimiento de análisis de imagen para cuantificar bandas fluorescentes de ácidos
nucleicos sobre electroforesis en geles en dos dimensiones. Investigación Clínica 2001;4:1-5.
19. Cerveri P, Masseroli M, Pinciroli F. Remote
access to anatomical information: an integration between semantic knowledge and
visual data. Journal of the
American Medical Informatics Association 2000;supplement
4/8-11-2000:126-130.
18. Ramírez
C, Olmo A, O'Valle F, Masseroli M, Aguilar M, Gómez-Morales M, Revelles
F, García-Chicano MJ, Arrebola F, Reguero ME, Del Moral RG. Role of intrarenal endothelin 1, endothelin
3, and angiotensin II expression in chronic cyclosporin A nephrotoxicity in
rats. Experimental
Nephrology 2000;8(3):161-172.
15. Bergeron C, Nogales FF, Masseroli M, Abeler V, Duvillard P,
Muller-Holzner E, Pickartz H, Wells M. A multicentric European study testing
the reproducibility of WHO classification of endometrial hyperplasia with a
proposal of a simplified working classification for biopsy and curettage
specimens. The American Journal Surgical Pathology 1999;23(9):1102-1108.
13. Vergara E, Gómez-Morales M, Osuna A, O'Valle
F, Aguilar D, Masseroli M, Martínez T, Asensio C, Del Moral RG. Immunohistochemical
quantification of leukocyte subsets in the long-term prognosis of kidney
transplants. Transplantation Proceedings 1998;30(5):2380-2383.
10. Masseroli
M, Cothren RM, Meier DS, Tuzcu EM, Vince DG, Nissen SE, Thomas JD, Cornhill
JF. Quantification of intramural calcification in coronary intravascular
ultrasound images with automated image analysis. American Heart Journal
1998;136(1):78-86.
8. Del Moral RG, Andújar M,
Ramírez C, Gómez-Morales M, Masseroli M, Aguilar M, Olmo A, Arrebola F,
Guillén M, García-Chicano MJ, Nogales F, O'Valle F. Chronic cyclosporin A
nephrotoxicity, P-glycoprotein overexpression, and relationships with intrarenal
angiotensin II deposits. The American Journal of Pathology
1997;151(6):1705-1714.
7. Pérez-Caballero C, Torres MPR,
Masseroli M, O'Valle F, García Del Moral R, Rodríguez Puyol M, Rodríguez
Puyol D. Papel de los inhibidores de la enzima de conversión de la angiotensina
en la prevención de las alteraciones renales asociadas al envejecimiento. Nefrología
1996;16(4):319-326.
6. O'Valle F, Mesa F, Aneiros J,
Gómez-Morales M, Lucena MA, Ramírez C, Revelles F, Moreno E, Navarro N,
Caballero T, Masseroli M, García Del Moral R. Gingival overgrowth
induced by nifedipine and cyclosporin A. Clinical and morphometric study with
image analysis. Journal of Clinical Periodontology 1995;22(8):591-597.
B. BOOKS
3. Elementi di Informatica BioMedica. Pinciroli F. Masseroli M,
editors. ISBN 88-7398-0171. Milano, IT: Polipress, 2005. (Scienze e Tecnologie
per la Salute).
2. Masseroli
M. Diseño y valoración de programas de
análisis digital de imagen y sus aplicaciones a la cuantificación automática de
patologías renales. PhD Thesis. University of Granada, Granada,
Spain; 1996.
1. Masseroli M. Elaborazione di bioimmagini: sviluppo di metodi e di
programmi su personal computer. Tesi di laurea. Politecnico di Milano,
Milano, Italia; 1990.
C. CHAPTERS IN BOOKS
15. Masseroli M, Paton
NW,
14. Masseroli M, Tagliasacchi M. Chapter 8: Web resources for
gene list analysis in biomedicine. In: Lazakidou A, editor. Web-based Applications in Health Care and
Biomedicine. ISBN 978-1-4419-1273-2.
13. Masseroli M, Ceri S,
Campi A. Integration and mining of genomic annotations: Experiences and
perspectives in GFINDer data warehousing. In: Paton NW, Missier P, Hedeler C,
editors. Data Integration in the Life
Sciences. Proceedings 6th International Workshop, DILS 2009, 2009 Jul
20-22;
12. Bonacina S, Privitera YA,
Marsilio S, Montin E, Passarelli F, Masseroli M, Pinciroli F. A
web-based tool for cooperating behaviors in eating and physical activity
control. In: Wiederhold BK, Riva G, editors. Annual Review of Cybertherapy and Telemedicine 2009 - Advanced
Technologies in the Behavioral, Social and Neurosciences. ISBN
978-1-60750-017-9.
11. Masseroli M, Ceri S. Bioinformatics for genomics and
proteomics. In: A. Cigada, editor. Nanomedicine.
Milano, IT: Politecnico di Milano, 2008. p. 15-18.
10. Ceresa M, Masseroli M. Chapter XI: Clinical and biomolecular
ontologies for e-health. In: Lazakidou AA, Siassiakos KM, editors. Handbook of Research on Distributed Medical
Informatics and E-Health. ISBN 978-1-60566-002-8.
9. Masseroli M. Mining
ed efficace utilizzo di informazioni in banche dati biomolecolari. In: Bellazzi R, Bicciato S, Cavalcanti
S, Cobelli C, Toffolo GM, editors. Genomica
e proteomica computazionale. ISBN:
978-88-555-2944-0. Bologna, IT: Pàtron editore, 2007. p. 379-415. (Gruppo
Nazionale di Bioingegneria; vol. 26).
8. Masseroli M. Capitolo 33: Banche dati e recupero delle
informazioni. In: Bernasconi C, editor. Predizione
molecolare e bioinformatica in ematologia/oncologia. Pavia, IT: Edizioni internazionali srl, 2007. p. 223-231. (Corsi di
formazione avanzata; vol 6/2007).
7. Maffezzoli A, Masseroli M. Chapter XLV: Genomic databanks for biomedical informatics. In: Lazakidou AA,
editor. Handbook of Research on
Informatics in Healthcare and Biomedicine. ISBN 1-59140-982-9.
Hershey, PA: Idea Group Inc., 2006. p. 357-366. (Medical Information
Science Reference).
6. Maffezzoli A, Masseroli M. Banche genomiche.
In: Pinciroli F. Masseroli M, editors. Elementi di Informatica BioMedica.
ISBN 88-7398-017-1. Milano, IT: Polipress, 2005. p. 165-213.
(Scienze e Tecnologie per la Salute).
5. Pinciroli F, Masseroli M,
Bonacina S. New e-health tracks in
engineering education of the Politecnico di Milano. In: Haux R,
Kulikowski C, editors. Ubiquitous Health Care Systems. Yearbook of Medical Informatics. ISBN 3-7945-2397-0. Stuttgart, D:
Schattauer Verlagsgesellschaft GmbH; 2005. p. 204-210.
4. Pinciroli F, Corbetta E,
Tamburini MF, Mattasoglio A, Bonacina S, Masseroli M, Meloni G,
Spaggiari P. Speak-ER: an audible web-based medical record for emergency
patients. In: Demiris G, editor. e-health: current status and future
trends. ISBN 1 58603 442 1. Amsterdam,
The Netherlands: IOS Press; 2004. p.
93-106. (Studies in
Health Technology and Informatics; vol 106).
3. Martucci D, Masseroli M, Pinciroli F. Gene Ontology application to
genomic functional annotation, statistical analysis and knowledge
mining. In: Pisanelli DM, editor. Ontologies in Medicine. ISBN 1-58603-418-9. Amsterdam,
The Netherlands: IOS Press; 2004. p.
108-131. (Studies in
Health Technology and Informatics; vol 102).
2. Masseroli M, Andújar M, Ramírez C, O'Valle F. Citometría digital y análisis de
imagen. In: Viguer JM, García Del Moral R, editors. Laboratorio
y Atlas de Citología. ISBN 84-486-0122-X. McGraw-Hill/Interamericana.
Madrid, Spain; 1995:264-280.
1. García Del Moral R,
O'Valle F, Masseroli M. Técnicas de análisis de imágenes en morfología
microscópica. In: García Del Moral R,
editor. Laboratorio de Anatomía
Patológica. ISBN 84-481-0229-0.
McGraw-Hill/Interamericana. Madrid, Spain; 1993:405-425.